The effect of lavender on Wounds healing

Burn is one of the leading causes of mortality in the world. Delay in wound healing can lead to poor anatomical outcomes, increase the risk of infection, and ultimately lead to dangerous complications and even death. Herbal preparations are among the Earliest methods adopted in episiotomy wound healing and pain relief. Wound diseases and inflammatory-related illnesses have been more common in recent Decades. Cure complexity, an increase in multidrug-resistant bacteria, side effects of medical therapies, and medication costs are both reasons for the need for the identification, and development of new, efficient treatments with low toxicity and low cost. Lavender, Lavandula angustifolia, is an herbaceous plant belonging to the mint family, Lamiaceae. Linalool and linalyl acetate are among the effective compounds of this plant with positive and significant effects on the gastrointestinal and central nervous systems. Therefore, our aim in this study was to investigate the effect of Lavender on the treatment of wounds.MethodFor this review, we conducted advanced research in PubMed, Google Scholar, and Science direct with “lavender” and “wound healing” key terms. After reviewing the relevant articles, ۱۷ articles were evaluated.resultsThe use of lavender oil showed a significant decrease in the area of the wound in rats. lavender oil-treated mice showed increased expression of both typ۱ I and II collagen, as the result of the increased number of fibroblasts, which synthesize collagen. Also, lavender oil increased the expression of TGF-β compared to the control, furthermore, the number of myofibroblasts increased which is needed for wound contraction via fibroblast differentiation by TGF- beta. Using lavender in combination with sesame oil showed significant improvement specifically in the accumulation of collagen, fibroblasts, and re-epithelialization.ConclusionLavender oil is an herbal extracted flower oil with different effects including antibiotic, antifungal, and sedative and also antimicrobial. This oil is effective in early wound healing. This essential oil also can use as an adjuvant agent or therapeutic alternative in surgical wounds but require skills and nursing care. Additional research and studies are needed to explore the different effects and mechanisms of this essential oil.

کلیدواژه ها:

Lavender ، Wound ، healing