The effect of aloe vera on wound healing after surgery: a systematic review

Background and purpose: Aloe vera is a herbaceous and perennial plant from the Liliaceae family. Many studies have been conducted on aloe vera and its topical use has been found to be useful in healing skin wounds. Based on this, we decided to conduct a systematic review of the effect of aloe vera on the healing of post-surgical wounds.Search method: by checking SID database, Irandoc, Google scholar, PubMed, Medline, Scopus, Science Direct, using the keywords "aloe vera", "wound healing"; All clinical trial articles that used aloe vera gel, cream, and other products derived from aloe vera, had a control group with placebo or compared with other treatments, were included in the study. Electronic search was done without any time limit. To carry out this review article, the ۲۰۰۹ PRISMA checklist was used, and articles that were conducted on animal samples, duplicate articles, articles with unclear statistical results, incomplete articles, and all articles with less than ۳۰ samples were removed.Results: Finally, ۱۶ clinical trials that met the inclusion criteria were examined. These studies have investigated the use of aloe vera in post-surgical wounds such as episiotomy, caesarean section, skin biopsy, hemorrhoidectomy, gynecological surgery laparotomy and graft site. In all these studies, the use of aloe vera gel and cream compared to other common treatments has reduced pain and discharge and reduced recovery time. In only one study, the aloe vera dressing group for shave skin biopsy did not differ from the combined dressing group in terms of recovery.Conclusion: According to the results of this study, the use of aloe vera is recommended as an effective and low-cost treatment for the revival of traditional medicine and as a complementary treatment.

کلیدواژه ها:

Aloe vera ، prevention ، wound healing after surgery ، systematic review