Synthesis of novel multifunctional pyrazole-tetrazole hybrids using magnetic nanocatalyst

سال انتشار: 1401
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 72

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شناسه ملی سند علمی:

CCMP01_066

تاریخ نمایه سازی: 8 مرداد 1402

چکیده مقاله:

In current report, the synthesis of novel multifunctional pyrazole-tetrazole derivatives was carried out by the reaction of diverse aryl aldehydes, malononitrile, phenylhydrazine and sodium azide in the presence of magnetic supported cobalt nanocatalyst (γ-Fe۲O۳@FAp@Co) in ethanol at room temperature. This method provided a novel approach for the synthesis of pyrzaole-tetrazole in excellent yield (۹۰–۹۵%) and short reaction time (۱۵-۲۵ min). The structures of prepared compounds were confirmed by analytical methods.

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نویسندگان

Samamne Jankianpour

Medicinal Chemistry Research Laboratory, Department of Chemistry, Guilan University

Manouchehr Mamaghani

Medicinal Chemistry Research Laboratory, Department of Chemistry, Guilan University

Iman Rezaei

Medicinal Chemistry Research Laboratory, Department of Chemistry, Guilan University