Effect of Bilva Herbal Ointment and Silver Sulfadiazine on Healing, Pain and Itching of Burn Wounds

Background: The most common method for burn wound dressing is silver sulfadiazine (SSD); however, its side effects on wound healing and the need for repeated use are often painful. This study sought to compare two different dressings, namely Bilva and SSD ointments, on wound healing, pain, itching, and scarring of burn wounds.Methods: This clinical trial was performed on ۳۵ patients with superficial second-degree burns hospitalized in the Burn Ward of Sina Hospital in Tabriz, Iran, from ۲۰۱۹ to ۲۰۲۰. After irrigation of the wound, Bilva ointment was applied randomly on one side and SSD ointment on the other side to treat the burns. Patients were followed on days ۱, ۷, ۱۴, ۲۱, and the first, second, and third months after burns;  data related to the wound healing process, pain, itching, and scar status of the patients were collected with a checklist. Results: There was no statistically significant difference between the two groups of variables related to the wound healing process on any of the time-points. The amount of burn wound scar did not differ between the two groups on day ۲۱ and the first, second, and third months. Pain and itching were significantly better in the Bilva group on the ۷th (p<۰.۰۱), ۱۴th (p<۰.۰۱), ۲۱st days (p<۰.۰۱), and the first month (p<۰.۰۱) after burns.Conclusion: Bilva ointment had a similar effect on healing of the burn wounds of patients compared to SSD, and it was more effective in controlling pain and itching of burn wounds. Further studies are needed to evaluate the cost-effectiveness of this dressing method on superficial burn wounds.

کلیدواژه ها:

Burn ، Silver Sulfadiazine Ointment ، Bilva Ointment