Inflammatory Factors and Their Association with Disease Severity in Patients with COVID-۱۹

Inflammatory factors play a very important role in causing inflammation. These inflammatory factors and proteins are the regulators of inflammatory responses. Considering the high transmission power and the pandemic caused by COVID-۱۹, it is necessary and important to determine the effective factors in the prognosis of this disease. Method: This study was carried out by descriptive method and based on secondary data analysis in the files of hospitalized patients with covid-۱۹ in the first six months of ۲۰۲۱ by census method. The data collection tool is a checklist (data collection form). Three categories of variables including epidemiological variables, clinical variables, and laboratory variables were extracted from the patient's files and analyzed. Results: The data of ۳۰۲ patients with COVID-۱۹ hospitalized in the ICU department of Peymaniyeh Hospital were collected. The majority of patients were over ۵۰ years old. There was no significant relationship between the severity of the disease and all of the demographic, clinical, and laboratory variables (P>۰.۰۵), except for the number of hospitalization days that in patients with severe disease, severity was significantly higher than in patients with moderate disease severity (P=۰.۰۰۱); CRP, ERS, and LDH in patients with severe disease severity were significantly higher than patients with moderate disease severity (P<۰.۰۵); But there was no significant relationship between other laboratory characteristics and disease severity (P<۰.۰۵). Conclusion: It can be concluded that patients over ۵۰ years of age who are admitted to the ICU require more careful care and elderly patients may have a higher chance of contracting COVID-۱۹.

کلیدواژه ها:

Inflammatory factors ، Disease severity ، Covid-۱۹.