Bivariate Survival Copula Analysis of Glaucoma Patients during Blindness: Glaucoma Cases at Alert Hospital in Addis Ababa City of Ethiopia
محل انتشار: مجله تحقیقات در علوم سلامت، دوره: 22، شماره: 2
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 93
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شناسه ملی سند علمی:
JR_JRHSU-22-2_003
تاریخ نمایه سازی: 28 تیر 1402
چکیده مقاله:
aimed to explore the dependence between blindness of the right and the left eyes of glaucoma patients and
assess the effects of the covariates under the dependence structure.
Study Design: A retrospective cohort study.
Methods: The study population included the glaucoma patients at Alert hospital from January ۱, ۲۰۱۸, to
December ۳۰, ۲۰۲۱. The copula model was used to estimate the time to the blindness of the right and the
left eyes of the glaucoma patients by specifying the dependence between the event times.
Results: Out of ۵۳۷ glaucoma patients, ۲۲۴ (۴۱.۷۱%) became blind at least in one eye during the followup
period. The results of the Clayton copula model revealed that factors, such as age, residence, diabetes
mellitus, stage of glaucoma, and hypertension are considered the most prognostic factors for blindness in
glaucoma patients. The findings also revealed that there was a strong dependence between the time to the
blindness of the right and the left eyes in the glaucoma patients (τ = ۰.۴۳).
Conclusion: Based on the obtained results, high age, urban residence, hypertension, diabetes mellitus, and
higher stage of glaucoma were factors associated with time to the blindness in the glaucoma patients. There
was also a dependence between the right and the left eyes of the glaucoma patients. The results revealed
that the Clayton Archimedean copula model was the best statistical model for accurate description of
glaucoma patients’ datasets.
کلیدواژه ها:
Background: Glaucoma is a worldwide problem that causes vision loss and even blindness ، with a
prevalence rate ranging from ۱.۹% to ۱۵%. In Ethiopia ، glaucoma is the fifth cause of blindness. This study
نویسندگان
Flromsa Shewa Gart
MSC, Department of Statistics, College of Natural and Computational Science, Assosa University, Assosa, Ethiopia
Gurmessa Nugussu Gelcho
MSc, Department of Statistics, College of Natural Science, Jimma University, Jimma, Ethiopia