Context: Although the current literature suggests the significant impact of the COVID-۱۹
pandemic on nosocomial infections, evidence
is still scarce in this regard.
Objectives: The present study aimed to systematically review the current literature to estimate the prevalence of hospital-acquired
infections (HAIs) and their determinants during the COVID-۱۹
Methods: A comprehensive search was conducted via electronic databases such as EMBASE, Google Scholar, Scopus, PubMed, and
Web of Science from the onset of the COVID-۱۹
pandemic until the end of June ۲۰۲۱. To estimate the pooled prevalence of nosocomial
infections, the random effects model was used.
Results: The prevalence of HAIs during the COVID-۱۹
pandemic was estimated at ۱۵% (۹۵% CI: ۹ - ۲۴). COVID-۱۹
for the highest infection rate in patients with HAIs (۶۳%; ۹۵% CI: ۴۳ - ۷۵), followed by bloodstream infections (۳۹%; ۹۵% CI: ۵۶ - ۲۴).
Among the common organisms that infected patients with HAIs, coronavirus had the highest rate (۶۳%; ۹۵% CI: ۴۳ - ۷۵), followed
by Enterococci and Enterococcus, respectively. In addition, positive significant correlations were observed between the prevalence of
nosocomial infections, age, and length of hospital stay (P < ۰.۰۵).
Conclusions: According to the results, nosocomial infections are an important consequence of the COVID-۱۹
in the elderly and high-risk populations with prolonged hospital stay. Therefore, the early detection of infected individuals could
be a key step toward improving the quality of response to the current pandemic.