On the Bioactivity and Mechanical Properties of Gehlenite Nanobioceramic: A Comparative Study

سال انتشار: 1399
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 91

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شناسه ملی سند علمی:

JR_JMSI-10-2_005

تاریخ نمایه سازی: 28 تیر 1402

چکیده مقاله:

Background: For a new biomaterial which is going to be applied in bone tissue regeneration, bioactivity (bone bonding ability) and desirable mechanical properties are very essential parameters to take into consideration. In the present study, the gehlenite's mechanical properties and bioactivity are assessed and compared with hydroxyapatite (HA) for bone tissue regeneration. Method: Gehlenite and HA nanoparticles are synthesized through sol–gel method and coprecipitation technique, respectively, and their physical and chemical properties are characterized through X‑ray diffraction, Fourier transform infrared spectroscopy, and transmission electron microscopy. Results: The results prove that the gehlenite and HA phases without any undesirable phase are obtained, and the particles of both compounds are in the nanometer range with spherical morphology. The compressive strength of both compounds are assessed, and the values for gehlenite and HA disks are ۱۴۴ ± ۵ and ۱۵۰ ± ۴.۸ MPa, respectively. Next, their bioactivity potential is assessed into simulated body fluid (SBF) up to ۲۱ days, and the results show that after ۱۴ days, gehlenite disk’s surface is completely covered with newly formed Ca‑P particles. However, some sporadic precipitations after ۲۱ days soaking into SBF are formed onto the HA disk’s surface. Conclusion: This comparative study shows that nanostructured gehlenite disk with desirable mechanical properties and faster bioactivity kinetic than HA can be considered as a promising bioceramic for bone tissue regeneration.

نویسندگان

Ashkan Bigham

Department of Materials Engineering, Advanced Materials Research Center, Najafabad Branch, Islamic Azad University, Najafabad

Saeed Kermani

Department of Bioelectrics and Biomedical Engineering, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences- Medical Image and Signal Processing Research Center, Isfahan University of Medical Sciences

Ahmad Saudi

Student Research Committee, School of Advanced Medical Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan

Amir Hamed Aghajanian

Department of Materials Engineering, Faculty of Engineering, Razi University, Kermanshah