Evaluation of the Lung Dose in Three‑dimensional Conformal Radiation Therapy of Left‑Sided Breast Cancer: A Phantom Study
سال انتشار: 1399
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 96
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شناسه ملی سند علمی:
JR_JMSI-10-1_006
تاریخ نمایه سازی: 28 تیر 1402
چکیده مقاله:
Background: Three‑dimensional ۳D-CRT: conformal radiation therapy is a selective modality
in many radiotherapy centers for the treatment of breast cancer. One of the most common side
effects of this method is radiation lung injury. Considering such an injury, lung dose deserves to be
studied in depth. Methods: Computed tomography scan of a node‑positive left‑sided breast cancer
woman was used for generating a thorax phantom. Ten thermoluminescent dosimeters (TLDs) were
distributed evenly in the left lung of the phantom, and the phantom was scanned. The optimal plan,
including supraclavicular and tangential fields, was created by the treatment planning system (TPS).
The results of TLD dose measurements at the selected points in the phantom were compared to
TPS dose calculations. Results: Lung doses calculated by TPS are significantly different from
those measured by the TLDs (P = ۰.۰۰۷). The minimum and maximum differences were −۰.۹۱%
and ۴.۴۶%, respectively. TLDs that were on the inner margin of the lung and breast tissue showed
higher dose differences than the TLDs in the lung. Conclusion: The results of this study showed that
TPS generally overestimated doses compared to TLD measurements due to incorrect beam modeling
caused by contaminated electrons in the lung.
کلیدواژه ها:
نویسندگان
Mahsa Abdemanafi
Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences
Mohammad Bagher Tavakoli
Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences
Ali Akhavan
Department of Radiotherapy Oncology, Seyed Alshohada Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
Iraj Abedi
Department of Radiotherapy Oncology, Seyed Alshohada Hospital, Isfahan University of Medical Sciences, Isfahan, Iran