Hematological Parameters Variations Among Patients With Uncomplicated Plasmodium falciparum Infection in Cambodia
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 79
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شناسه ملی سند علمی:
JR_IJTMGH-10-2_005
تاریخ نمایه سازی: 7 تیر 1402
چکیده مقاله:
Introduction: The prevalence of anemia among patients with malaria is very common from subsequent erythrocytes destruction and should be managed most appropriately. This study aimed to explore the changes in hematological parameters and their underlying influence among people with uncomplicated Plasmodium falciparum infection.Methods: A cross-sectional study was conducted among uncomplicated malaria patients infected by P. falciparum on community-based active screening days in one of the highest malaria hot-spot areas of northwestern Cambodia. Descriptive statistics, and student t-tests were used to analyze the data.Results: Among ۱۰۳ malaria blood samples, the results showed that most participants had thrombocytopenia (۸۴.۵%). More than one-half of the participants presented normal levels of the following hematological parameters: red blood cells, hemoglobin, hematocrit, mean corpuscular volume (MCV) and red cell distribution width (RDW). A significant correlation was noted between parasite counts and three body mass index (BMI) groups (P=۰.۰۴۷). Next, a strong association was also seen between parasite counts and body temperature (P=۰.۰۳). Statistically significant differences in parasite count were observed across three levels of neutrophil (P=۰.۰۰۵), lymphocyte (P=۰.۰۰۱), eosinophil (P<۰.۰۰۱), absolute lymphocyte (P=۰.۰۰۱) and absolute eosinophil (P<۰.۰۰۱) counts.Conclusion: The results of this study revealed the significant role of hematological parameters in predicting the presence of malaria infection, parasite density, and forecasting adverse consequences of malaria, together with the underlying risk factors.
کلیدواژه ها:
نویسندگان
Rathvicheth Bun
Public Health Office, Faculty of Public Health, Mahidol University, Bangkok, Thailand
Bui Thi My Anh
Public Health Office, Faculty of Public Health, Mahidol University, Bangkok, Thailand
Kyaw Ko Ko
Public Health Office, Faculty of Public Health, Mahidol University, Bangkok, Thailand
May Chan Oo
Public Health Office, Faculty of Public Health, Mahidol University, Bangkok, Thailand
Kyaw Zarni Tun
Public Health Office, Faculty of Public Health, Mahidol University, Bangkok, Thailand
Myat Thu Soe
Myanmar Health Network Organization, Yangon, Myanmar
Pyae Aung
Public Health Office, Faculty of Public Health, Mahidol University, Bangkok, Thailand