COVID-۱۹ and Brain complications in adult and pediatric patients: A review on neuroimaging findings

In this review, we will discuss the neuroimaging findings of patients with COVID-۱۹ from the outbreak (late December ۲۰۱۹) to the end of October ۲۰۲۱. PubMed, Scopus, Google Scholar, Science Direct, ProQuest, Web of Science and the World Health Organization database (January ۰۱, ۲۰۲۰, to October ۳۰, ۲۰۲۱) were searched for related published articles. In each of the databases, the appendix search strategies were performed and the below keywords were used: COVID-۱۹”OR“coronavirus disease ۲۰۱۹” AND “brain MRI” OR “brain magnetic resonance imaging” OR “brain CT” OR “neuroimaging”. In total, neuroimaging findings of ۱۵۵۰ patients, with ages from ۱-۹۶ years, were analyzed. Most brain neuroimaging findings include hyperintensity, Cerebral venous thrombosis, intraventricular and subarachnoid hemorrhage, infarction, leukoencephalopathy, acute ischemic strokes and posterior reversible encephalopathy syndrome (PRES) in adult patients and severe encephalopathy, stroke, infarction, CNS infection/demyelination, neuritis or polyradiculitis, venous thrombosis, Guillain-Barré syndrome, and longitudinally extensive myelitis, and myositis in pediatric patients. Our findings showed that the most important complication of the coronavirus is not just respiratory complications, because although transiently, COVID-۱۹-related brain complications are seen in pediatrics as well as adults, and families should pay more attention to health care.

کلیدواژه ها:

brain MRI ، Cerebral Hemorrhage ، Coronavirus disease ، neuroimaging ، SARS-CoV-۲ ، Subarachnoid Hemorrhages