Effect of Androgen Use among Children with Micropenis in Erbil City

Background and objective: Micropenis is a condition where the penis is smaller than average, causing psychological distress and affecting sexual function. The aim of this study was to determine the effect of androgen therapy on gonadal response and penis growth in children with micropenis.Method: This was a retrospective and prospective study including a sample of ۳۰ children in the age range of ۹-۱۳ years old with micropenis from March ۲۰۱۹ to December ۲۰۲۲ in Erbil, Iraq. Informed consent was obtained from the legal guardian of the children. Demographic information, drug dosage, testosterone level, and penis length were collected and recorded before and after the therapeutic intervention. All participants received a therapeutic regimen involving Sustanon ۲۵۰ mg/۱ml injections.Result: In this study, the age of the patients participating in the study was between ۹ and۱۳ with an average (standard deviation) of ۱۱.۱۷۶ ± ۰.۵۶۷ years old. The number of treatment doses varied, with ۱۶.۷% receiving one dose, ۳۳.۳% receiving two doses, and ۵۰% receiving three doses. Testosterone levels significantly increased from a mean of ۰.۰۲۴ ± ۰.۰۰۷ ng/dl before the intervention to ۰.۸۸۳ ± ۰.۳۱۸ ng/dl after (p ≤ ۰.۰۰۱). In addition, penile length significantly increased from a mean of ۱۶.۹۸۳ ± ۱.۹۲۳ mm before the intervention to ۳۶.۷ ± ۳.۴۸۵ mm after (p ≤ ۰.۰۰۱).Conclusion; Androgen can be useful in the treatment of micropenis because the results showed that it increased both the testosterone level and the penis length.

کلیدواژه ها:

Androgen ، Child ، Hormone ، Sustanon