Comparison of polymorphism in vitamin D gene and interleukin ۱۰ in healthcare workers

Despite all the efforts made, many cases of disease are reported. Examining the various dimensions of factors affecting the infection, mutation, etc. of the virus in people with covid-۱۹ and healthy people can be effective in finding a solution for these hypotheses. According to this topic, the role of vitamin D in getting the disease or facilitating the disease process was investigated. In this study, Blood samples in the control and patient groups are examined to check the polymorphism in vitamin D. The gene polymorphism is determined and the PCR product is determined by restriction enzyme and the length of the polymerase chain reaction fragment (PCR-RFLP) is determined by polymorphism. SPSS is used for statistical analysis. Considering all the cases of investigating polymorphisms and mutations in different parts of interferon among patients with covid-۱۹,, as well as examining genes such as vitamin D, their importance in the immune system has been less investigated is very important We observed significant differences in genotypes vit D receptor in two group healthcare worker with Covid-۱۹ and cases control.

کلیدواژه ها:

polymorphism ، Covid-۱۹ ، vitamin D receptor