Malignant Hyperthermia, Cardiac Dysrhythmia and Hypertension Crisis in Sublingual Misoprostol: Educational Policy for Adverse Drug Reaction Organization
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 169
فایل این مقاله در 9 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_JOGCR-8-1_015
تاریخ نمایه سازی: 9 اردیبهشت 1402
چکیده مقاله:
Pyrexia and shivering are the most popular side effects of postpartum administration of misoprostol, but other side effects of this drug are very rare. A ۲۷-year-old pregnant female patient was admitted to Ayatollah Mousavi hospital (Zanjan, Iran), complaining about severe headache and the primary diagnosis of cerebral venous thrombosis. Treatment was successful after primary investigations and planed therapy for Cerebral Venous Thrombosis (CVT). Following the decision on terminating the pregnancy, five tablets of Sublingual misoprostol (۲۰۰ mg) was used once evacuation of pregnancy remnants was done. About thirty minutes after the administration of misoprostol, onset of severe shivering and tachycardia (۲۰۱/min) with high fever (about ۴۱°C) and hypertension (۱۸۲/۱۲۳ mmHg) was observed. National Adverse Drug Reaction (ADR) form was completed. All of symptoms were alleviated ۳۰ minutes after administration of Paracetamol ۱gram (Intravenous infusion) followed by Metoprolol ۵۰ mg (orally). According to the literature, we listed the various side effects of misoprostol. Even though the side effects of misoprostol are diverse and rare, the simultaneous occurrence of these side effects is not cited till date. These incidents are reported to the authorities as per ADR policy; nonetheless, no preventive measures are implemented. This necessitates medical educational policies to be taken into consideration to educate healthcare providers throughout their professional career as well as research.
کلیدواژه ها:
نویسندگان
Mohammad Reza Zeraati
Department of Anesthesiology, Ayatollah Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran
Hojjat Torkmandi
Department of Operating Room, Faculty of Nursing and Midwifery, Zanjan University ofMedical Sciences, Zanjan, Iran
Mohammad Abdi
Ph.D Candidate of Medical Education, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
Mohammad Reza Jamshidi
Department of Cardiac Anesthesiology, Ayatollah Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran
Alireza Safaie
School of Science, Engineering and Environment, University of Salford, Manchester, UK
مراجع و منابع این مقاله:
لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :