The effect of Epimedium on infertility treatment

Introduction: If a couple does not become pregnant after one year of frequent unprotected sex,the couple is considered infertile. In the world, ۱۸۶ million people, ۵۱% of whom are couples,are infertile. Studies show that infertility is one of the most important issues for individuals andfamilies that has increased in recent years. Medicinal herbs have been used to treat variousdiseases for many years in eastern countries, including China. Epimedium is one of these plantsthat is used in the treatment of various diseases, including infertility. Therefore, our goal inthis study is to investigate the effect of Epimedium on the treatment of infertility.Method: The research in this article was obtained by searching databases such as GoogleScholar, PubMed, and, Science Direct. The keywords "infertility," "Epimedium," and "treatment" are used. Finally, ۱۷ articles were analyzed .Results: Studies show that a mixture of ۲ herbal extracts, KH-۴۶۵, which consisted ofEpimedium koreanum Nakai and Angelica Gigas Nakai, may reduce the effects of oxidativestress on spermatogenesis. In male mice, tramadol (TAM) reduces sperm motility and counts.The extract Epimedium brevicornum Maxim can alleviate some of these negative effects.Premature ovarian insufficiency (POI) may be affected by epimedium through biologicalprocesses, cell components, molecular functions, and signaling pathways. According to thestudies, epimedium contained multiple compounds and acted on POI targets in multiple ways.Conclusion: Today, infertility is regarded as a disease affecting society, with various treatmentmethods available. Based on a systematic review of studies conducted, Epimedium can treatinfertility through several mechanisms, but more studies are needed .

کلیدواژه ها:

Epimedium ، infertility ، treatment