The prognostic value of kidney failure based on glomerular filtration rate in predicting long in-hospital outcomes in patients with unstable angina

سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 157

فایل این مقاله در 7 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

JR_CBJ-2-2_007

تاریخ نمایه سازی: 21 فروردین 1402

چکیده مقاله:

Objectives: Numerous recent studies have emphasized the role of kidney failure in developing ischemic heart disease (IHD) and the resulting adverse consequences. The purpose of the present study was to quantitatively assess the effect of kidney failure based on glomerular filtration rate (GFR) in predicting clinical outcomes in patients with unstable angina (U/A).Methods: This retrospective cohort study included ۱۲۹ patients with unstable angina with preserved left ventricular function. Serum creatinine levels were specified at the beginning of their admission. The GFR at admission time was determined based on the MDRD index. Based on the GFR value, patients were classified into two groups, i.e., normal GFR (>۶۰) and decreased GFR (<۶۰).Results: The frequency of one-month mortality in <۶۰ GFR and >۶۰ GFR was ۳.۲% and ۰.۰%, respectively. Furthermore, the prevalence of ۶-month mortality in <۶۰ GFR and >۶۰ GFR was ۸.۱% and ۰.۰%, respectively. The frequency of readmission in <۶۰ GFR and >۶۰ GFR was ۲۹% and ۱۱%, respectively. Likewise, the frequency of revascularization through coronary artery bypass graft (CABG) or percutaneous coronary intervention (PCI) in <۶۰ GFR and >۶۰ GFR was ۲۵.۸% and ۸.۹%, respectively. According to the multivariate logistic regression model, <۶۰ GFR increased the risk of ۶-month mortality up to ۰.۲ times (probability ratio of ۲.۰۸۱, P-value of ۰.۰۲۳). Regarding readmission, <۶۰ GFR increased the need for readmission up to ۲.۴ times (probability ratio of ۲.۴۳۳, P-value of ۰.۰۴۹). On the other hand, the risk of CABG or PCI recurrence following initial intervention was ۲.۸ times higher in patients with <۶۰ GFR than in the >۶۰ GFR group (probability ratio ۲.۸۸۲, p-value .۰۳.Conclusions: The study revealed that <۶۰ GFR compared to higher values ​​of GFR is associated with an increased risk of ۶-month mortality, increased readmission, and increased revascularization in patients with unstable angina.

نویسندگان

Venus Shahabi Raberi

Seyed-Al-Shohada Cardiology Hospital, Urmia University of Medical Sciences, Urmia, Iran

Razieh Parizad

Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

Reza Faramarz Zadeh

Seyed-Al-Shohada Cardiology Hospital, Urmia University of Medical Sciences, Urmia, Iran

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • M C Foster, D E Weiner, A G Bostom, et ...
  • Levey AS, Coresh J, Tighiouart H, et al. Measured and ...
  • Ying T, Gill J, Webster A, et al. Canadian-australasian randomised ...
  • Sarnak MJ, Amann K, Bangalore S, et al. Chronic kidney ...
  • Chen J, Budoff MJ, Reilly MP, et al. Coronary artery ...
  • Al‐Naher A, Wright D, Devonald MAJ, et al. Renal function ...
  • Jenkins R, Mandarano L, Gugathas S, et al. Impaired renal ...
  • Shlipak MG, Heidenreich PA, Noguchi H, et al. Association of ...
  • Thakar CV, Christianson A, Freyberg R, et al. Incidence and ...
  • Mullens W, Damman K, Testani JM, et al. Evaluation of ...
  • Karki P, Agrawaal K, Lamsal M, et al. Predicting outcomes ...
  • Lin T-H, Hsin H-T, Wang C-L, et al. Impact of ...
  • El-Menyar A, Zubaid M, Sulaiman K, et al. In-hospital major ...
  • Al Suwaidi J, Reddan D, Williams K, et al. Prognostic ...
  • Nabais S, Rocha S, Costa J, et al. Prognostic impact ...
  • Sooklim K, Srimahachota S, Boonyaratavej S, et al. Renal dysfunction ...
  • Anavekar NS, McMurray JJ, Velazquez EJ, et al. Relation between ...
  • نمایش کامل مراجع