Serotonin syndrome in a young adult through single serotonin-modifying agents

مقدمه : Serotonin syndrome can be a serious complication of treatment with selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants, monoamine oxidase inhibitors (MAOIs), and other serotonergic medications. The syndrome is characterized by the sudden onset of cognitive/behavioral changes, autonomic instability and neuromuscular changes. It usually occurs when ۲ or more serotonin-modifying agents are used in combination; however, cases have been reported after single agent therapy.هدف : This case illustrates the importance for clinicians to monitor for signs of serotonergic toxicity even in patients who are only taking a single serotonergic medication.معرفی بیمار : A ۱۹ year-old female with a history of major depression since a year ago referred to Kowsar hospital from Shariati hospital of Karaj on ۱۴۰۱/۰۱/۲۹. She was complaining of anxiety, vertigo (worsening due to closing eyes), and tachycardia since ۵ hours ago and had a history of taking ۱۰ pills of LAMOTRIGIN, ۱۰ pills of ESCITALOPRAM and ۲۰ pills of MODAFINIL on the day of admission.

کلیدواژه ها:

Serotonin syndrome ، serotonin toxicity ، serotonin reuptake inhibitors