Cost and Early Complication Analysis Following Total Hip Arthroplasty in Parkinson’s Disease Patients: A Propensity-matched Database Study

Background: Parkinson’s Disease is a well-known neuromuscular disorder, which affects the stability and gait of elderly patients. With the progressive increase in the life span of patients with PD, the problem of degenerative arthritis and the consequent need for total hip arthroplasty (THA) in this cohort are rising. There is paucity of data in the existing literature regarding the healthcare costs and overall outcome following THA in PD patients. The current study was planned to assess the hospital expenditure, details regarding hospital stay, and complication rates for patients with PD, who underwent THA. Methods: We investigated the National Inpatient Sample data to identify PD patients, who underwent hip arthroplasty from ۲۰۱۶ to ۲۰۱۹. Using propensity score, PD patients were matched ۱:۱ to patients without PD by age, gender, non-elective admission, tobacco use, diabetes, and obesity. Chi-square and T-tests were used for analyzing categorical and non-categorical variables, respectively (Fischer-Exact test was employed for values<۵).Results: Overall, ۳۶۷,۸۹۰ (۱۹۲۷ patients with PD) THAs were performed between ۲۰۱۶ and ۲۰۱۹. Before matching, PD group had significantly greater proportion of older patients, males, and non-elective admissions for THA (P<۰.۰۰۱). After matching, PD group had higher total hospital costs, longer hospital stay, greater blood loss anemia, and prosthetic dislocation (P<۰.۰۰۱). The in-hospital mortality was similar between the two groups. Conclusion: Patients with PD undergoing THA required greater proportion of emergent hospital admissions. Based on our study, the diagnosis of PD showed significant association with greater cost of care, longer hospital stay, and higher post-operative complications. Level of evidence: II

کلیدواژه ها:

Parkinson’s disease ، Total hip arthroplasty