Introduction- Bioactive peptides (BP) are low molecular weight protein fragments of ۲–۲۰ amino acids residues thatexhibit beneficial physiological effects in human. BP as the new generation of biologically active regulators; havehormonal or pseudo-pharmacological activities, which are classified into antimicrobial, antithrombotic,antihypertensive, opioid, immunotherapeutic, and antioxidative groups, thus increasing the quality of life. In Islamiclifestyle,
Tayyeb is the highest level for food quality which has ۵ aspects included nutritious and safety, being halal,originality, attractiveness and blessing. So, focus on high nutritional value of foods that can guarantee the health of the consumer is important. Use of food products with bioactive peptides or the isolated and purified BP from foodproteins as additives can provide the nutritious and safety aspect of
Tayyeb products. Numerous bioactive peptideshave been reported in recent years as naturally present or generated from food proteins of different origins like milk,eggs, soya, fish, and meat. BPs remain inactive while the sequences are kept within the parent protein and they activeonce released by enzymatic hydrolysis by peptidases during gastrointestinal digestion and/or during food processingsuch as fermentation.Material and Methods (Or Methodology)- related articles from ۲۰۱۰ to ۲۰۲۲ were searched in Google Scholar,PubMed, Web of Science databases. Among the ۱۸ articles found in this regard, ۸ related papers were used.Conclusion - Nowadays, there is an increasing commercial interest in the production of BP from varioussources due to the wide range of health-promoting properties of biopeptides and this fact that BP have the potential tobe used as food additives and ingredients of pharmaceuticals for the treatment or prevention of some medicalconditions and life style diseases, such as obesity, diabetes type II and hypertension. The use of food biopeptides hasbeen declared safe for consumers, but the safety of purified and synthesized biopeptides must be evaluated beforecommercialization because there still are several obstacles to overcome, particularly from the technological viewpointto produce them at large scale without losing activity. Although several studies have shown non-toxicity properties ofBP in the cell culture, direct studies should be done on the human body to find the molecular mechanisms of theseinteractions and use them as a tool to improve human health.