The therapeutical potency of cyanobacterial secondary metabolites compared with chemotherapy against leukemia: Mini-review

Cyanobacteria are a significant group of gram-negative photosynthetic bacteria which havethe ability to grow in a broad range of habitat such as lakes, oceans, soil, hot springs,deserts and so on. These photosynthetic organisms are known a potential source ofbioactive compounds that can be generated as byproducts during photosynthetic processwith antibacterial, anti-tumour, neuroprotective, and anti-cancer activities. So far,several cyanobacterial bioactive compounds with anti-leukemia activities have beenevaluated for treatment of leukemia which is one of the most common leading cause ofcancer death. However, no review study has been conducted about the anti-leukemiacyanometabolites and their therapeutic mechanisms. Therefore, this review discussesfive major striking anti-leukemia cyanometabolites and their therapeutic mechanisms insummarize. Ultimately, the traditional therapeutic procedure, chemotherapy, and itscommon challenges and issues have been investigated to declare the superiority ofnatural medicines over chemotherapy.

کلیدواژه ها:

Cyanobactria ، Algae ، Cancer ، Leukemia ، Chemotherapy