Enantioselectivity of imine reductase enzymes in the asymmetric synthesis of cyclic amines

سال انتشار: 1401
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 2,098

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شناسه ملی سند علمی:

CCES17_015

تاریخ نمایه سازی: 19 آذر 1401

چکیده مقاله:

The field of organic chemistry has produced numerous essential daily-use essential products.The detrimental consequences of the chemical industry on the environment have promptedconsiderable changes in the production of chemicals. Biocatalysis offers an alternative tostandard synthetic approaches by utilizing enzymes, nature's catalysts, in place of artificialcatalysts to produce chemical changes. Enzymes are biodegradable, created from renewableresources, and exhibit excellent selectivity in the reactions they catalyze. Biocatalysis is ahighly interdisciplinary field that has profited substantially from recent discoveries in, amongother disciplines, molecular biology, bioinformatics, and chemical engineering. This researchfocused on the enantioselectivity of imine reductases (IRED), the configuration of finalproducts, and their chiral products' enantiomeric excess (ee).

نویسندگان

Hossein Mahmoodian

Department of Chemistry, Payame Noor University, P.O.BOX: ۱۹۳۹۵-۳۶۹۷,Tehran, Iran

Ghasem Rezanejade Bardajee

Department of Chemistry, Payame Noor University, P.O.BOX: ۱۹۳۹۵-۳۶۹۷,Tehran, Iran

Mohammadreza Zamani

Department of Chemistry, Payame Noor University, P.O.BOX: ۱۹۳۹۵-۳۶۹۷,Tehran, Iran

Hamid Saeidian

Department of Chemistry, Payame Noor University, P.O.BOX: ۱۹۳۹۵-۳۶۹۷,Tehran, Iran

Seyed Ata Boraghi

Department of Chemistry, Payame Noor University, P.O.BOX: ۱۹۳۹۵-۳۶۹۷,Tehran, Iran