Synthesis of Substituted Triazoles Using a New Deep Eutectic Solvent and a MagneticallyReusable Fe۳O۴@SiO۲@PrNCu Nanocatalyst

Heterogeneous copper-catalyzed Click cycloaddition of alkyl halides, sodium azide, and terminalalkynes was perfomed and improved to be more economical and environmentally friendly by using agreen deep eutectic solvent (DES) and Fe۳O۴@SiO۲@PrNCu, as the magnetic catalyst. A new DESwas designed which hydrophobic/hydrophilic balance of it, enabled easier association of polar ornonpolar reactants during the reaction than conventional green but only polar solvent such as waterand also provides better diffusion onto the nanocatalyst's surfaces, resulting accelerates the catalyticprocess. Simple experimental procedures accompanied by utilization of new DES and reusablenanocatalyst could be considered as alternative features of this new protocol to the existing methodsfor the Cu-catalyzed Click cycloaddition reaction

کلیدواژه ها:

Deep eutectic solvent ، Magnetic nanocatalyst ، Copper catalyst ، Click reaction