Concordance between TIRADS and Cytology in Thyroid Nodule

Introduction:Palpable thyroid nodules are stated in ۴ to ۷% of individuals. This study was designed to evaluate the relation of Thyroid Imaging Reporting and Data System (TIRADS) and fine-needle aspiration (FNA) based cytology reports in patients with thyroid nodules.Materials and Methods:In this retrospective cross-sectional study, individuals with thyroid nodules who were selected for ultrasonographic-guided FNA enrolled in this study. Demographic data, radiologic assessment, and cytology report were gathered based on hospital medical records. TIRADS grading of the nodules was assessed for each nodule. Cytology was performed on all samples. Sensitivity and specificity were calculated by comparing cytology with ACR-TIRADS and also cytology with TIRADS ۴-۵ cut-off point as a radiologic malignant lesion.Results:۱۷۲ patients were studied, ۱۵۱ of whom were female and ۲۱ were male. The mean age of the patients was ۴۹.۴۶ years. Most of the patients had TIRADS ۴ (۵۳.۵%) followed by ۳ (۳۱.۴%), and ۵ (۱۱.۶%). ۱۵۱ patients (۸۷.۸%) had a benign lesion in cytology. Of them, ۱۱۸ had colloid nodules. There was a statistically significant relation between TIRADS and cytology (p-value<۰.۰۰۱). Sensitivity, specificity, AUC, and positive and negative predictive value for ACR-TIRADS classification were ۷۶.۱۹%, ۴۷.۵۴%, ۰.۶۱۹, ۲۰.۰۰%, and ۹۲.۰۶%, respectively. These values for cut-off “۴-۵” classification was ۸۶.۳۶%, ۳۸.۰۰%, ۰.۶۲۲, ۱۶.۹۶%, and ۹۵.۰۰%.Conclusions:According to the significant concordance between TIRADS and cytology, as shown in the results of our study, it seems that TIRADS could be used to decrease the amount of unnecessary FNA in individuals with thyroid nodules.

کلیدواژه ها:

Fine-needle aspiration ، Thyroid nodule ، Ultrasonography ، TI-RADS ، Biopsy