Mortality Rate of COVID‐۱۹ Patients in Intensive Care Unit: A Multicentre Retrospective Observational Study

The case of Coronavirus Disease ۲۰۱۹ (COVID-۱۹) is growing rapidly worldwide. More than ۶ million people in Indonesia were confirmed to be infected as of March ۲۰۲۲. This disease caused an increase in the demand of respiratory assistance and intensive care services back in ۲۰۲۱. Unfortunately, the report about COVID-۱۹ case in Intensive Care Unit (ICU) of Indonesia is very scarce although it is very crucial to evaluate the treatment approach and the prognosis of the patients. This study aimed to determine the characteristics, therapy, and outcomes of critically ill COVID-۱۹ patients treated in the ICU. This was a multicentre retrospective study conducted in ۱۲ hospitals in Indonesia from April ۲۰۲۰ to March ۲۰۲۱. All data regarding the characteristics, therapy, and outcomes of COVID-۱۹ patients admitted to ICU were recorded and analysed. ۱,۵۰۲ patients were included in this study. Inpatient mortality occurred in ۴۴.۶۷% patients. The highest morbidity is attributed to stroke (۸۳.۴%). We found a significantly longer duration of mechanical ventilation use in non-survivors group (۵.۵۷ vs. ۱.۷۴ hours). Furthermore, the results of this study showed a significant difference in all type of treatment (excluding antifungal) between two groups. The mortality of COVID-۱۹ patients in ICU is considerably high. Hypothyroidism and DMIІ patients showed a high serum asprosin, which linked with poor glycemic and lipid management. It is a biomarker for diabetes and thyroid issues.

کلیدواژه ها:

COVID ، ۱۹ Mortality ، intensive care