COVID-۱۹ Treatments Based on Pathogenicity

سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 101

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شناسه ملی سند علمی:

JR_IEJM-11-3_007

تاریخ نمایه سازی: 3 آبان 1401

چکیده مقاله:

The new coronavirus was first identified in China in December ۲۰۱۹ and then, it created a widespread pandemic around the world. There is currently no definitive cure for it and it will not be possible to make a vaccine soon. Pathogenic mechanism of the virus includes virus entry, binding to angiotensin-converting enzyme ۲ (ACE۲) receptors on the surface of host cells, proliferation, membrane fusion, assembly, subsequent infection, cytokine secretion, and the host immune response to the virus. By identifying at what stage the patient is, possible effective drugs can be used to control each stage. Therefore, identifying the mechanism of action of the virus in different stages of the disease makes it possible to use the appropriate drug for each stage of the disease and control the disease.

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نویسندگان

Ali Salimi Asl

نویسنده اول

Faezeh Malekzadeh

نویسنده دوم

Amin Reza Nikpoor

نویسنده سوم

Shaghayegh Kermaninezhad

نویسنده چهارم

Sobhan Montazerghaem

نویسنده مسئول