Study of phenotypic antimicrobial resistance tocephalosporins in Shiga toxin-producing Escherichia coli strains isolatedfrom sheep carcasses in Kerman

Background and Aim : Shiga toxin-producing Escherichia coli (STEC) are one of the mostimportant food-borne pathogens associated with fecal contaminations in the foods produced byanimals. The present study was carried out in order to study of phenotypic resistance tocephalosporins (cefixime and cephalexin) in STEC strains isolated from sheep carcasses inKerman.Methods : In this study ۳۰ STEC isolates were confirmed by conventional PCR methods. Diskdiffusion technique was used to analyze STEC isolates for resistance against cefixime andcephalexin.Results : Among the ۳۰ STECs, ۲۴ (۸۰%) were resistant to the cephalexin and ۱۷ (۵۶.۶%) wereresistant to the cefixime. Also, ۶ isolates (۲۰ %) were evaluated as sensitive to cephalexin and ۹isolates (۳۰ %) were evaluated as sensitive to cefixime.Conclusion : The results of this study show that STEC strains obtained from raw sheep meat havesignificant resistance to cefixime and cephalexin, which potentially threatens public health.

کلیدواژه ها:

Shiga toxin-producing ، Escherichia coli ، Sheep ، Antibiotic resistance ، cephalosporins.