Antimicrobial effect of Alternaria metabolite isolated fromtomato on Staphylococcus aureus

Background and Aim : Antimicrobial effect of Alternaria metabolite isolated from tomato onStaphylococcus aureusMethods : To evaluate the antimicrobial effects, the diameter of inhibitory zone was measuredusing disk diffusion and agar diffusion methods. In addition, the minimum inhibitory concentration(MIC) and Minimum bactericidal concentration (MBC) were determined by macro dilutionmethod.Results : Disk diffusion results shows that no inhibitory zone for extract against S. aureus in ۱۱۰,۱۲۰ and ۱۵۰ μl. Agar diffusion results shows no inhibitory zone in ۱۷۰, ۲۰۰ and ۲۲۰ μl for S.aureus. MIC was ۵۰۰ mg/ml and MBC was ۰ mg/ml.Conclusion : Based on data, Alternaria metabolites had antimicrobial effect against S. aureus butnot strong.

کلیدواژه ها:

Antimicrobial effect ، S. aureus ، Alternaria ، Metabolites