The effects of aqueous and alcoholic extracts of Nymphaeaalba on Candida albicans and determine effective products andcomparing the results to clotrimazole

Background and Aim : The effects of aqueous and alcoholic extracts of Nymphaea alba onCandida albicans and determine effective products and comparing the results to clotrimazoleMethods : In this study, the aqueous, ethanolic and methanolic extracts of Nymphaea alba werestudied on Candida albicans with disc, wells, minimum inhibitory concentration (MIC) andminimum fungal concentration (MFC) concentrations. Also, the amount of active component inNymphaea alba essential oil was measured by gas chromatography (GC). ۶,۷-Dimethoxy-۲-methyl-۱ with ۲۰.۲۴% was the most active component in Nymphaea albaResults : The average of growth inhibitory diameter for the aqueous, ethanol and methanol extractsin the well method was ۱۳.۹۲, ۱۷.۷۵ and ۱۵.۷۵ mm, respectively. Meanwhile, in the wellscontaining clotrimazole, the absence of growth was ۴۵ mmConclusion : The aim of this study was to investigate the effect of Nymphaea alba aqueous andalcoholic extract on Candida albicans. In this study, the aqueous, ethanolic and methanolic extractsof Nymphaea alba were studied on Candida albicans with disc, wells, minimum inhibitoryconcentration (MIC) and minimum fungal concentration (MFC) concentrations

کلیدواژه ها:

Nymphaea alba ، Candida albicans ، Antifungal activity ، Clotrimazole