Survey of plasma alterations of hepcidine, cholinesterase andtotal sialic acid in sheep with naturally infected Sarcocystosis

Background and Aim : Sarcocystis parasitic protozoa are one of the most common parasites ofdomestic animals and in some intermediate hosts such as cows and sheep it leads to severeinfections due to the direct relationship of these animals with humans, infestation in humansocieties is also an important health problem. The present study was also conducted with the aimof studying the plasma changes of hepcidin, cholinesterase, and total sialic acid in sheep sufferingfrom Sarcocystis. Considering that hepcidin generally plays an active role in the pathologicalprocess of many iron disorders in the body, it is expected that the measurement of its concentrationin the biological fluids of the body will help in the diagnosis of diseases. Cholinesterase is one ofthe most important enzymes that is needed for the proper functioning of the nervous system. Sialicacids are present in many mammalian tissues so their concentration increases in inflammatorydiseases and other diseases.Methods : In this study, blood samples were taken from ۸۰ sheep affected with Sarcocystis andwere analyzed in two groups, control, and patient.Results : The statistical results show that the studied parameters in the sick sheep had a significantincrease compared to the control group (P<۰.۰۵).Conclusion : The results show that there is a significant increase in the level of enzymes studiedin the patient's group compared to a healthy group, which can be used to diagnose this disease.

کلیدواژه ها:

Sarcocystosis ، Hepcidine ، Cholinesterase ، Total Sialic Acid ، Sheep