Investigation of the frequency of Helicobacter pylori infectionin tissue samples of gastric cancer in Tabriz hospitals

Background and Aim : Gastric cancer is one of the most common cancers of the gastrointestinaltract and the second most common cause of cancer-related deaths worldwide, and various factorssuch as Helicobacter pylori ( H. pylori)infection play a role in its occurrence. The purpose of thisstudy is to investigate the prevalence of H. pylori in gastric cancer tissue samples in Tabrizhospitals.Methods : In this descriptive cross-sectional study, ۵۰ gastric cancer tissue samples were collectedalong with ۵۰ non-cancerous samples as positive controls from Tabriz hospitals. The samples wereexamined using rapid urease test and culture and pathological examination for H.pylori. SPSSversion ۲۰ software was used for data analysis.Results : In this study, ۱۰۰ cancerous and non-cancerous samples were compared in terms of H.pylori prevalence. The prevalence of H. pylori was ۶۰% in the cancer group and ۳۰% in the noncancergroup. There was no significant relationship between age and gender in the prevalence ofH. pylori (p> ۰.۰۵).Conclusion : There is a direct relationship between gastric cancer and H. pylori. Identification ofqualitative criteria for the diagnosis of Helicobacter pylori infection is required.

کلیدواژه ها:

Gastric cancers ، infection ، Helicobacter pylori