Investigation of frequency and determination of drugsensitivity of Gram-positive bacteria causing septicemia in Inhospitalized patients of HAJAR Hospital, Shahrekord , Chaharmahaland Bakhtiari Province , ۱۴۰۰ .

Background and Aim : Blood infections are increasingly reported in the world , since Since theyare important diseases, targeted antimicrobial treatment can reduce complications in patients withsepticemia. In order to have a targeted treatment, it is necessary to accurately identify the bacteriaand effective antibiotics for its treatment . Gram-positive bacteria are also one of the causes of thisinfection, research and investigation on these bacteria and identifying the most effective antibioticsfor treatment and ,as a result, reducing mortality are very important. Therefore, the purpose of thisstudy is to investigate the frequency and determine drug sensitivity of Gram-positive bacteriacausing septicemia in hospitalized patients of HAJAR Hospital, Shahrekord , Chaharmahal andBakhtiari Province in ۱۴۰۰ .Methods : In this cross-sectional-retrospective study, all blood cultures referred to Hajar hospitallaboratory from April to March ۱۴۰۰ were examined and studied . Blood cultures were cultured instandard Blood Agar and Chocolate Agar environments and bacterial growth was checked after ۲۴to ۴۸ hours . Based on the type of bacteria grown, antibiotic sensitivity was evaluated on Mueller-Hinton's culture medium in the form of disk diffusion using commercial and standard disks.Finally, the findings were analyzed using descriptive statistics.Results : The results of this study showed that out of ۶۳۷۶ blood cultures, ۱۷۰ samples werepositive (۲.۶۶%). Among them, ۶۷ cases (۳۹.۴۱%) were infected with gram-positive bacteria. Theantibiogram results showed the highest sensitivity to Linezolid (۹۷.۶۲%), rifampin (۸۶.۱۱%),amikacin (۷۳.۶۸%) and cefoxitin (۷۳.۰۸%), respectively. In this study, the most drug resistanceswere erythromycin (۸۴.۰۹%), ciprofloxacin (۵۲.۶۳%) and cefoxitin (۲۵%).Conclusion : Conclusion: According to the results, most gram positive bacteria wereStaphylococcus species. By analyzing antibiotics, it can be said that ciprofloxacin can still be usedfor septicemia caused by gram positives.

کلیدواژه ها:

septicemia ، gram positive bacteria ، blood culture ، drug sensitivity