Bacterial community of chronic rhinosinusitis patients andtherapeutic ultrasound efficacy: clinical trial study

Background and Aim : Bacterial involvement in chronic rhinosinusitis (CRS) condition made itdifficult to treat using available antibiotic therapy. Therapeutic ultrasound was investigated hereto evaluate bacterial diversity and quantity before and after continuous/pulsed ultrasound strategycompared to control patients.Methods : Totally, ۳۴ CRS patients were studied in three groups, including continuous ultrasound,pulsed ultrasound and control. Bacterial culture and identification were done before and aftertreatment. Computed tomography scan (CT scan) and questionnaire scores were recorded twotimes before and after intervention.Results : The most prevalent bacterial isolates were non-hemolytic Streptococci (۳۴ patients),coagulase-negative Staphylococcus (۳۳ patients), Gram-negative cocci (۲۶ patients),Staphylococcus aureus (۱۹ patients), Streptococcus pneumoniae (five patients) and Streptococcuspyogenes (five patients). Both continuous and pulsed ultrasound could significantly reduce thequantity of bacterial isolates after treatment. CT scan and questionnaire results support theeffectiveness of therapeutic ultrasound.Conclusion : The quantity of clinically important bacteria was significantly reduced usingultrasound treatment and recovery of patients was supported by CT scan and questionnaire scores.Alternative therapeutic ultrasound could be an effective procedure in CRS patients.

کلیدواژه ها:

Rhinosinusitis ، Ultrasound therapy ، Bacterial infection ، Treatment ، Computedtomography scan