Investigating in-vitro antimicrobial activity, biosynthesis, andcharacterization of silver nanoparticles, zinc oxide nanoparticles, andsilver-zinc oxide nanocomposites using Pistacia Atlantica Resin

Background and Aim : Background: In the present study, a fast and straightforward method waspresented for the preparation of silver nanoparticles (AgNPs), zinc oxide nanoparticles (ZnNPs),and silver-zinc oxide nanocomposites (Ag-ZnNPs).Methods : Methods: Biosynthesis was carried out using resin extraction from Pistacia Atlanticaas a reductant and capping agent. In-vitro antimicrobial activities of these particles, silver nitrate(AgNO۳), and zinc nitrate (Zn (NO۳)۲) were also evaluated in comparison with resin extracts.Synthesis of the nanoparticles and nanocomposites was characterized and confirmed byultraviolet-visible spectroscopy (UV–vis), X-ray diffraction n (XRD), Fourier-transform infraredspectroscopy (FTIR), field emission scanning electron microscopy (FESEM) equipped with anenergy dispersive spectroscopy (EDS) and transmission electron microscope (TEM). Then,antimicrobial activity was tested against Klebsiella pneumonia, Escherichia coli, Staphylococcusaureus, and Proteus mirabilis using the agar well diffusion method.Results : Results: Maximum inhibition zones were observed for resin-AgZnNPs and resin-ZnNPs(۲۱.۱ ± ۰.۰۰۲ mm), demonstrating their antibacterial activity, while Zn (NO۳)۲ had the smallestinhibition zone (۵.۴ ± ۰.۰۶ mm).Conclusion : Conclusions: These results are promising in terms of their potential ability to be usedagainst pathogenic bacteria.

کلیدواژه ها:

Pistacia atlantica resin extract ، Nanoparticles ، Nanocomposite ، Antibacterial activity