NOVEL ANTIMICROBIAL WITH ACTIVITY AGAINST MDRGRAM NEGATIVE BACTERIA

Background and Aim : In recent years several novel antimicrobials with activity againstmultidrug-resistant Gram-negative bacilli have become available. Among the novel antimicrobialsare ceftazidime-avibactam, meropenem-varborbactam, imipenem-relebactam and cefiderocol. Thenovel antimicrobials rarely cover all bacterial resistance mechanisms and it is of utmost importanceto use them rationally. This presentation reviews the activity of the novel antimicrobial as well asthe potential for resistance development. Methods for reliable antimicrobial susceptibility testingare also presented, and it is emphasized that susceptibility cannot be assumed, but needs to beconfirmed by testing. The presentations also briefly discusses some antimicrobials that are still inthe development pipeline.Methods : -Results : -Conclusion : -

کلیدواژه ها:

multidrug-resistant