ANTIBACTERIAL RESISTANCE IN PEDIATRIC BURN PATIENTS

Background and Aim : Burn injuries are a global public health problem and still remain theleading cause of disability and unintentional death.Methods : The risk of infections is relatively high due to the immunosuppressing effect of burns,invasive therapeutical procedures, and length of hospitalization. In pediatric burn patients,mortality rates due to sepsis still remain high. Infected burn wound serves as an important sourcefor most of the cases of sepsis.Results : The development of antibiotic resistance causes a big challenge in the treatment ofbacterial infections in both adult and pediatric patients. Furthermore, resistance to multipleantibiotic classes reduces the probability of adequate empirical coverage, with possibleunfavorable outcomes. Vulnerability to infections and increasing antibiotic resistance amongorganisms put burn patients at high risk of infection by multidrug-resistant (MDR) organisms.Hospital cleaning practices, antibiotic therapy without knowledge of circulating bacterial strains,and excessive and prolonged use of antibiotics have led to the development and selection ofmultidrug-resistant bacteria. The MDR/XDR/PDR gram negative bacteria, MRSA/VRSA/VREhave become increasingly common in hospital settings, necessitating the understanding ofinstitutional specific circulating strains.Conclusion : Moreover, healthcare professionals managing burn patients require in-depthknowledge of bacteria causing infection and their antimicrobial resistance patterns to directempirical therapy.

کلیدواژه ها:

Antibacterial resistance ، pediatric ، burns