Diabetes is one of the health challenges for decades, which is concurrent with many pathological disorders. Hence so the aim of the current study aims is to clarify the relationship between type ۲ diabetes and peptic ulcers, in addition to knowing its causes and ratio among the population of Wasit city. This study was conducted on ۱۰۰ patients with type ۲ diabetes aged between ۲۰-۸۰ years and ۵۰ non-diabetics with a peptic ulcer as a control group. Medical and laboratory tests to identify diabetes mellitus and peptic ulcers were conducted in at Al-Zahraa General Teaching Hospital. The current study showed that most of the diabetic patients are in the age group from ۶۰ to ۸۰ years, and most of the patients were males (۵۳%). The results of the present research showed that the main leading cause of type ۲ diabetes are is a family genetic predisposition to diabetes (۴۴%). Also, exposure of some individuals to a sudden psychological or nervous shock had a role in the occurrence of diabetes by ۲۴%. In our research, ۵۵% of the diabetic patients suffer from peptic ulcers (۵۵/۱۰۰ persons) and mainly appeared among males (۲۹ males (۵۳%)) compared to females (۲۶ females (۴۷%)). The clinical and laboratory tests showed that Helicobacter pylori (H. pylori) infections were more virulent on in the digestive system of diabetic patients compared to the than non-diabetic patients. The results showed that the occurrence of peptic ulcers in both the stomach and duodenum appeared clearly in diabetic patients, where whereas ۴۲% of diabetic patients had simultaneous ulcers in the stomach and duodenum at the same time. The
endoscopic test detected that high-risk hemorrhage Forrest IA, IB, and llA were mainly identified in diabetic patients at a percentage of ۱۸.۵%, ۱۵%, and ۱۳%, respectively. Patients with type ۲ diabetes have a significant risk for of developing peptic ulcer hemorrhage.