What Is Hemophilia?

Hemophilia is usually an inherited bleeding disorder in which the blood doesnot clot properly. This can lead to spontaneous bleeding as well as bleedingfollowing injuries or surgery. Blood contains many proteins called clottingfactors that can help to stop bleeding. People with hemophilia have low levelsof either factor VIII (۸) or factor IX (۹). Hemophilia is caused by a mutationor change, in one of the genes, that provides instructions for making theclotting factor proteins needed to form a blood clot. In rare cases, a person candevelop hemophilia later in life. The majority of cases involve middle-aged orelderly people or young women who have recently given birth or are in thelater stages of pregnancy. This condition often resolves with appropriatetreatment. classic hemophilia, or hemophilia A, is caused by a mutation in thegene encoding coagulation factor VIII (F۸; ۳۰۰۸۴۱) on chromosome Xq۲۸.This article deals with issues like the definition of hemophilia, its symptoms,and its genetic causes.

کلیدواژه ها:

Hemophilia ، Protein ، factor VIII ، factor IX ، Genes