The Effects of Celery (Apium graveolens L.) Extract on Some Biochemical Parameters in Rats That Consume a Concentrated Feed

The purpose of this study was to examine the liver function effects of aqueous celery extracts on liver function tests and lipid profile in rats. A total of forty rats were split into four classes, ۱۰ rats per category, fed for ۳۰ days as Group A: received regular diet, Group B: received concentrated feed diet, Group C: received ۲۰% celery extract in the regular diet, Group D: received a concentrated feed diet with ۲۰% celery extract. The levels of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), and lipids profile have been also determined in all subjects. The results indicated significant variations at (P≤۰.۰۵) between tested groups for triglycerides, total cholesterol, and HDL levels in the blood serum, except in rats group B, the group D recorded a high levels of lipid profile, while the lowest value has been reported in group A. The results indicated that rats group C compared with B over an experimental duration had low triglycerides, average cholesterol, and high-density lipoprotein (HDL) amounts. Also, AST and ALT were substantially reduced in D. Based on the results, it was clear that celery can reduce the lipid profile levels and it has hepatoprotective effects by decreasing AST and ALT enzymes.

کلیدواژه ها:

Celery extracts ، Rats ، Diet ، Liver function ، lipid profile