How nanotechnology can be effective in control of the COVID-۱۹ pandemic

Introduction: The coronavirus disease-۲۰۱۹ (COVID-۱۹) pandemics caused by the severe acute metabolic process syndrome coronavirus a pair of (SARS-CoV-۲) has been spreading round the world because of its high infection rate, long period, similarly as lack of effective designation and medical aid or vaccines, that is tearing world health systems apart. Key components are bestowed here to raised perceive the link between nanomedicine and also the COVID-۱۹. We discuss recent similarly as current nanotechnology-based therapeutic and prophylactic ways to fight against this pandemic, outlining the key areas for Nano scientists to step in. The review is predicted to alter researchers to grasp the result of nanomaterials for the designation and medical aid of COVID-۱۹ and should turn breakthroughs during this space.Search Method: PubMed, Google Scholar and Scopus were used for comprehensive searches for articles printed by ۲۰۲۱. Keywords enclosed nanomaterials, COVID-۱۹, SARS-CoV-۲ and nanomedicine. We selected the articles based on the title and abstract. Finally, we found ۶ articles with our selection criteria.Results: Nanomaterials provided a strong platform to neutralize completely different infective agent infections, like respiratory disease or MERS coronaviruses. The S macromolecule of SARS-CoV a pair of plays a important role in its infection mechanism. Supported the interaction between S macromolecule and ACE۲ on the host cytomembrane, already existing antiviral nanomaterials may be wont to treat COVID-۱۹. Furthermore, this PIH/Au nanomaterial show high stability with potential applications for similar coronaviruses. Additionally to kill the virus within the body, nanomaterials will stop the virus entry into the cells. Recently, inhaled silver nanoparticles (Ag NPs) were used as a primary line approach for the treatment and hindrance of COVID-۱۹ infection progression. In addition to speedy designation, creating recommendations to physicians regarding speedy treatment ways will save the lives of the many folks. To identify and monitor the progress of COVID-۱۹, subgenus Chen And colleagues rumored a speedy lateral flow at the purpose of care Lanthanide-doped polystyrene-based bioassay Nanoparticles for the detection of anti-SARV-CoV-۲ immune {serum globulin |immune gamma globulin |immune globulin} in human serum in ten minutes. To avoid interference from alternative viruses, Moitra and colleagues developed gold nanomaterials combined with the antisense oligonucleotides specific for N-gene of SARSCoV-۲ infective agent ordination to by selection sight positive COVID-۱۹ patients at intervals ten min by a quantitative analysis assay. Conclusion: Increasing proof indicates that nanomaterials may provide new insights to develop novel delivery systems or kill viruses directly. The inherent chemicophysical properties of nanomaterials, e.g., low toxicity, ultra-small dimension, high specific expanse, chemical modification capabilities, and high reactivity, play a important role in point-of-care designation and intriguing nanosystems for COVID-۱۹ treatment. First, an in depth body of labor is needed to elicit the underlying mechanisms of the interactions between nanomaterial interface and SARS-CoV-۲, tracing an inexpensive style of COVID-۱۹ medicine. Second, to enhance the potency of COVID-۱۹ medicine in vitro and in vivo, high-throughput ways are expected to be designed.

کلیدواژه ها:

Nanomaterials ، COVID-۱۹ ، SARS-CoV-۲ ، nanomedicine