Accuracy of Paris ۲۰۱۶ System for Non-invasive Diagnosis Bladder Malignancy

Background & Objective: The Paris System for Reporting Urinary Cytology (TPS) is a new method for evaluating urinary cytology designed to reduce unreproducible reports. The aim of this study was to reclassify and compare urinary cytology reports with TPS criteria to determine the frequency of unreproducible reports compared to the previous system.Methods: In this study, the laboratory electronic registration system analyzed patients' urine samples taken by voided or washing and brushing methods. The cytological evaluation was performed considering the previous system and TPS by a pathologist. The results of the two systems were compared, and the sensitivity and specificity of TPS were calculated.Results: Urine samples were taken from ۸۷۶ patients. The mean age of patients was ۶۳.۳۶ ± ۱۲.۶۲. Comparing the routine classification system and TPS, it was observed that the number of atypical reports in the TPS system decreased by ۱۲%, and all of these cases were downgraded to the negative group in the new classification. The sensitivity and specificity of TPS were ۲۹.۴% and ۹۵.۱%, respectively, if suspected malignancy and positive reports for malignancy were considered. Finally, if positive reports for malignancy were selected, sensitivity and specificity changed to ۱۱.۸% and ۱۰۰%, respectively.Conclusion: Although the TPS system has low sensitivity for the diagnosis of urothelial malignancies, due to its high specificity, it is possible to consider and use this classification for screening patients.

کلیدواژه ها:

Paris system ، Sensitivity ، Specificity ، Urine Cytology