Evaluation of the Relationship Between Serum and Urine Ferritin Level of Low Birth Weight Infants
محل انتشار: فصلنامه آسیب شناسی ایران، دوره: 17، شماره: 3
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 189
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شناسه ملی سند علمی:
JR_IJP-17-3_009
تاریخ نمایه سازی: 8 شهریور 1401
چکیده مقاله:
Background & Objective: Iron deficiency before birth or in infancy can cause long-term behavioral and neurological disorders. Measuring serum ferritin is an effective way to diagnose iron deficiency but requires significant blood volume from a low birth weight infant. Therefore, the present study was performed to investigate the relationship between serum and urinary ferritin levels in low birth weight infants.Methods: In this cross-sectional study, ۷۶ infants weighing less than ۲۵۰۰ g were studied. To measure serum ferritin level, ۱.۵ mL of blood and to measure urinary ferritin level, at least ۱ mL of urine was collected from each infant. Then the results were compared. Data analysis was performed using SPSS software version ۱۶, and the significance level was considered less than ۰.۰۵.Results: Out of ۷۶ neonates studied, ۵۱.۳% were boys, and ۸۰.۳% were premature infants. The mean birth weight of infants was ۲۰۵۶.۳۱±۳۱۸.۷۴ g, and the mean serum and urinary ferritin levels were ۱۳۴.۷۷±۷۲.۳۵ and ۸۵.۵۵±۷۰.۹۷ ng, respectively. There was a statistically significant relationship between serum and urinary ferritin levels. Also, serum ferritin and urinary ferritin levels had a statistically significant relationship with birth weight and gestational age. The higher the birth weight as well as the age at birth, the higher the serum ferritin and urinary ferritin.Conclusion: According to the findings of this study, measurement of urinary ferritin level can be used as a noninvasive tool for iron deficiency screening in low birth weight infants instead of serum ferritin level.
کلیدواژه ها:
نویسندگان
Hassan Bazmamoun
Department of Pediatric Gastroenterology, Hamadan University of Medical Sciences, Hamadan, Iran
Soheila Narimani
Department of Pediatrics, Hamadan University of Medical Sciences, Hamadan, Iran
Maryam Shokohi
Department of Neonatal-Perinatal Medicine, Hamadan University of Medical Science, Hamadan, Iran
Hossein Esfahani
Department of Pediatric Hematology/Oncology, Hamadan University of Medical Science, Hamadan, Iran
Ali Soltanian
Department of Biostatistics, Hamadan University of Medical Sciences, Hamadan, Iran
Alireza Rastgoo Haghi
Department of Pathology, Hamadan University of Medical Science, Hamadan, Iran
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