Immediate results and six-month outcomes after percutaneous coronary intervention in a referral heart center in Isfahan, Iran

BACKGROUND: There is a lack of data in our society on the outcomes, complications, and prognostic factors in patients with coronary artery disease who underwent percutaneous coronary intervention (PCI). We evaluated the success rate, early and late outcomes, and prognostic factors in a referral university center in Isfahan, IRAN.    METHODS: This prospective cohort study was conducted in Chamran University Hospital in Isfahan (IRAN) from March ۲۰۱۰ to February ۲۰۱۱. Patients consequently were included if they have the indication for emergent or elective PCI. Outcomes included procedural success, complications, and major adverse cardiovascular events (MACE) during hospitalization and ۶ months follow-up.    RESULTS: A total of ۲۸۲ patients (۷۴.۱% females) with mean age of ۵۷.۰±۳.۲ years were studied. Most of the patients (۸۹.۷%) underwent elective PCI. Angiographic and procedure success rates were ۹۵.۷% and ۹۴.۶%, respectively. In-hospital MACE included two cases of death (۰.۷%) and one MI (۰.۳%); ۲/۲۹ (۶.۹%) of the emergent PCI and ۱/۲۵۳ (۰.۴%) of the elective PCI cases. MACE during follow-up included three cases of death (۱.۰%) and two MI (۰.۷%); ۲/۲۵۲ (۰.۸%) of the elective PCI and ۱/۲۸ (۳.۵%) of the emergent PCI cases. The overall MACE was calculated as ۸ cases (۲.۸%) which included ۵/۲۹ (۱۷.۲%) of the emergent and ۳/۲۵۳ (۱.۱%) of the elective cases; P < ۰.۰۰۱. In multivariate analysis, none of the factors including gender, age, emergency of the procedure, lesion type, number of stenotic vessels, or stent type were associated with total MACE (P > ۰.۰۵).    CONCLUSION: PCI is performed with an acceptable success rate in our center in Isfahan and mortality and complications are within the range reported by other highly specialized centers in IRAN. Further studies with larger sample size are needed to find predictive factors.Keywords: Percutaneous coronary intervention, Myocardial infarction, Acute coronary syndrome, Reperfusion therapy, Outcome, Mortality.