Association between ABO blood group and severity of coronary artery disease in unstable angina

BACKGROUND: ABO blood groups are genetically transmitted through chromosome ۹ at locus ۹q۳۴. It is supposed that there is a locus on ۹p۲۱, which has a role in developing coronary artery disease. METHODS: Our study population consisted of ۳۰۹ patients with unstable angina admitted to the Ziaeian Hospital, Tehran, Iran, who underwent coronary angiography. The association between types of blood group (O and non-O) with the severity of coronary artery disease was investigated. RESULTS: Compared to the non-O groups, the O group had more severe coronary artery involvement (P = ۰.۰۰۴). CONCLUSION: Our study supports recent suggestions on the association between blood group and coronary artery disease. Further studies are needed to evaluate the effect of blood group on atherosclerosis.  

کلیدواژه ها:

ABO Blood Group System ، Blood Group ، Coronary Artery Disease ، Unstable Angina ، Acute Coronary Syndrome ، Myocardial Ischemia ، Angina Pectoris ، Atherosclerosis