J wave syndrome: Benign or malignant?

J wave syndrome is an electrical disease of the heart due to pathologic early repolarization. It encompasses a clinical spectrum from aborted sudden cardiac death due to ventricular arrhythmia (VA) usually in young affected patients to self-terminating ventricular ectopies, and finally, asymptomatic relatives of probands detected during electrocardiography acquisition (early repolarization pattern). This syndrome consists of ۲ phenotypes, early repolarization and Brugada syndrome. Herein, we first describe ۲ patients with early repolarization and Brugada syndrome, then, discuss their definition, epidemiology, genetics, cellular mechanism, diagnosis, risk stratification, and finally, therapeutic challenges and options one by one in detail.

کلیدواژه ها:

Brugada Syndrome ، Sudden Cardiac Death ، Ventricular Tachycardia