Evaluating value of positive T wave in lead V۱ and TV۱ > TV۶ pattern in predicting significant coronary artery disease in patients undergoing coronary angiography

BACKGROUND: The aim of this study was to predict significant coronary artery disease (CAD) in patients undergoing coronary angiography.METHODS: In this cross-sectional study, data of ۳۸۴ patients who underwent angiography during ۲۰۱۵-۲۰۱۷ were reviewed. Electrocardiograms (ECGs) were evaluated in terms of having positive T wave in lead V۱ (TV۱) described as T wave with amplitude of more than ۰.۱۵ mV and angiography records were assessed for presence of significant CAD defined as presence of ≥ ۷۰% internal diameter stenosis in at least one major epicardial coronary artery or more than ۵۰% stenosis in left main artery (LMA).RESULTS: Out of ۳۸۴ patients who participated in this study with mean age of ۶۳.۶ ± ۱۰.۲ years (۴۰-۸۹ years), ۷۱.۶% showed positive TV۱ and significant CAD simultaneously and left anterior descending artery (LAD) and left circumflex artery (LCX) lesions were more frequently reported in coronary angiography. Based on chi-square test, the prevalence of significant CAD was obviously more in those with positive TV۱ as compared to those without this finding [odds ratio (OR) = ۲.۷۴, ۹۵% confidence interval (CI): ۱.۸۰-۴.۱۹, P < ۰.۰۰۱]. Mann-Whitney test showed significant difference in number of coronary arteries involved in CAD between presence of positive and negative T wave in lead V۱ (P < ۰.۰۰۱). Great number of patients with significant CAD had remarkably higher T wave amplitude in lead V۱ in comparison to lead V۶ (OR = ۶.۲۲, ۹۵% CI: ۳.۱۴-۱۲.۳۰, P < ۰.۰۰۱).CONCLUSION: Positive TV۱ and TV۱ > TV۶ pattern can be considered as a predictor forsignificant CAD in patients with otherwise normal ECG.

کلیدواژه ها:

Coronary Artery Disease ، Electrocardiography ، Angiography