The interference effect of gold nanoparticle with blood erythropoietin level

Introduction: Erythropoietin is an important renal hormone that plays an important role in renal endocrine regulation. The erythropoietin is essential for the management of anemia in renal failure case. Additionally, monitoring of blood erythropoietin level is a routine practice in diagnosis and follow-up of management in patients with anemia.Objectives: Similar to any laboratory investigation, an important consideration in erythropoietin measurement is the laboratory interference in analytical process.Patients and Methods: In this study, the authors perform an experimental study to assess the effect of gold nanoparticle on the blood erythropoietin level.Results: Results showed significant interference. In the present day, the new nano-substances are widely used including new drugs.Conclusion: The interference of nanoparticle becomes an interesting issue that the practitioner should recognize and aware during application of blood erythropoietin level. The gold nanoparticle can alter the blood erythropoietin level in laboratory investigation. This should be an important consideration in the present day that there are many newly available nanosubstances.

کلیدواژه ها:

Erythropoietin ، Laboratory ، Gold nanoparticle ، Interference