Alkaline Catalyst-Free Homo- and Cross- Oxidative Coupling of Benzylic and Quasi Benzylic sp³ Bonds with O۲

An efficient and convenient approach to construct Csp۳–Csp۳ bonds via catalyst-free KOH-MeOH/air mediated oxidative homo- and cross-coupling reaction was reported. In this study, benzylic and quasi-benzylic reactants, such as toluene, pyridine, and quinoline derivatives were used to perform an oxidative coupling reaction via convenient air oxygen. The corresponding products were obtained with reasonable yields.

کلیدواژه ها:

Oxidative coupling ، Air Oxygen ، C–C bond ، benzylic and quasi benzylic ، sp۳ bond