Prevalence of psychiatric disorders in multiple sclerosis patients: A cross-sectional study

Introduction and Objective: The incidence risk of psychiatric disorders is higher in patients with multiple sclerosis (MS) than in the general population. This cross-sectional study aimed to evaluate the frequency of psychiatric disorders in patients with MS referring to Sina Hospital in Hamadan, western Iran, from ۲۰۱۶ to ۲۰۱۹. Materials and Methods: This cross-sectional study was performed on ۹۵ patients with MS referring to Sina Hospital in Hamadan, ۲۰۱۶-۲۰۱۹. Demographic information, illness duration, and psychiatric disorders were collected using the Symptom Checklist-۹۰-Revised (SCL-۹۰-R) questionnaire in ۲۰۱۶-۲۰۱۷. Data were analyzed in SPSS software (version ۱۶) using the Chi-square test and Spearman correlation coefficient. Results: The most common psychiatric disorders in these patients were found to be depression in ۳۶ (۳۹.۱%) cases, phobic anxiety in ۳۳ (۳۴.۷%) subjects, and somatization in ۳۳ (۳۴.۷%) patients. The least prevalence rates of the disorders were reported for psychoticism in ۱۷ (۱۷.۹%) cases and paranoid ideations in ۱۸ (۱۸.۹%) cases. In all psychiatric disorders, except obsessive-compulsive disorder, the frequency of psychiatric disorders was higher in women than in men (۲۷.۱% vs. ۱۳.۸%), and the only significant difference between the two groups was observed in the anxiety dimension (P=۰.۰۰۲). There was a significant positive correlation between the mean scores of the global severity index and the Expanded Disability Status Scale (r=۰.۴۱, P =۰.۰۰۱). Conclusion: The findings of this study showed that in patients with MS, depression, somatization, and phobic anxiety were the most common psychiatric disorders that were associated with increased severity of the disability.

کلیدواژه ها:

Multiple sclerosis ، Neurology ، Prevalence ، Psychiatric disorders ، urology