Green synthesis of silver nanoparticles using aqueous extract of Thymus kotschyanus Boiss & Hohen and study of their antibacterial potential

The synthesis of silver nanoparticles (AgNP) is a very promising technique because of its wide applicability, especially in the treatment against pathogen microorganisms. The antimicrobial activity from AgNP is mainly due to their large surface area, which results in greater interaction between the nanoparticles and the cells of the microorganisms, inhibiting their growth even at very low concentrations in the medium. In this research Ag NPs are synthesized successfully using flavonoid rich extract of Thymus kotschyanus aerial parts as an environmentally friendly alternative to the toxic chemical reducing agents. The Ag NPs obtained are characterized by ultraviolet-visible (UV–Vis) spectrometer, field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR). FE-SEM analysis revealed the shape of Ag NPs being spherical morphology with an average size range of ۲۰–۲۵ nm. Moreover, Ag NPs prepared in this manner exhibited good antibacterial activity toward Gram-positive (Bacillus subtilis and Staphyloccocus aureus) and Gram-negative (Escherichia coli and Pseudomonas aeruginosa) bacteria, and hence have potential applications in biomedical field

کلیدواژه ها:

antibacterial potential ، green synthesis ، silver nanoparticles ، Thymus kotschyanus.