Co(II), Ni(II) and Cu(II) Mononuclear Complexes with N۲O۲ Ligand Derived from Ethyl ۴-Aminobenzoate

By condensation reaction between P-amino benzoic acid and ethanol in the presence of concentrated H۲SO۴ to produce ethyl ۴-aminobenzoate, which was then converted into N, N'-(۱,۲-phenylene) bis(۴-aminobenzamide) type [H۲L] (N۲O۲) product by direct interaction between the two reactive molecules of this product with one molecule of ۱,۲-Benzene diamine, as a new series of metal conversion complexes of Co(II), Ni(II), and Cu(II). The prepared ligand and their complexes characterized in the solid and solution states using spectroscopic techniques such as UV-Vis, FT.IR, ۱HNMR, and the elemental analyses as well as melting temperatures, molar conductivity, and magnetic susceptibility. The octahedral geometry around the central metal is suggested by molar conductivity, magnetic moment, molar ratio, and spectroscopic data about copper and cobalt ions, while tetrahedral around the nickel ion. After the incubation period at ۳۷ °C for ۲۴ h, the biological behavior of the binding produced with its anti-bacterial compounds against (Staphylococcus aureus and Escherichia coli) was examined at different concentrations (۱۰, ۵۰, and ۲۰۰) ppm. The results showed that the performance of the prepared compounds was better in resisting and reducing the growth of bacteria tested at high concentrations.

کلیدواژه ها:

Metal ions ، Chelation ، Amides derivatives ، Anti-bacterial activity